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Application of Correlation Abstract Correlation is a statistical method used to assess a possible linear association between two continuous variables. It is simple both to calculate and to interpret. However, misuse of correlation is so common among researchers that some statisticians have wished that the method had never been devised at all. The aim of this article is to provide a guide to appropriate use of correlation in medical research and to highlight some misuse. Examples of the applications of the correlation coefficient have been provided using data from statistical simulations as well as real data. Rule of thumb for interpreting size of a correlation coefficient has been provided. Definitions of Correlation and Clarifications The term correlation is sometimes used loosely in verbal communication. Among scientific colleagues, the term correlation is used to refer to an association, connection, or any form of relationship, link or correspondence. This broad collo